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NCIRE Investigators

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Alan B.C. Dang

MD

Staff Surgeon, Orthopaedic Spine Surgery, SFVAHCS

Assistant Professor in Residence, Department of Orthopaedic Surgery, UCSF

Dr. Dang’s research seeks to develop new methods and techniques for studying biomechanics after an an acute, traumatic injury on the battlefield as well as the consequences of chronic wear and tear that reflects normal aging. He was the first researcher in the USA to be granted access to Toyota Motor Company's digital human model (THUMS) and modify the automotive safety tool for use in orthopaedic research to use computer modeling and simulation to study spinal biomechanics.

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Alexander Monto

MD

Director, Liver Clinic, SFVAHCS

Associate Professor of Clinical Medicine, UCSF

Dr. Monto has been involved with the national VA Hepatitis C Resource Center Program since its inception in 2001. He has co-written many national VA management recommendations, including those related to hepatitis C management, cirrhosis, and liver cancer. His research focuses on liver disease progression related to chronic hepatitis C infection, and particularly the role of co-factors (alcohol intake, intrahepatic fat, HIV infection, anti-HCV therapy) in altering disease progression.

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Alexis Dang

MD

Staff Surgeon, Orthopedic Sports Medicine, SFVAHCS Assistant Professor in Residence, Department of Orthopedic Surgery, UCSF

Dr. Dang’s clinical interest revolves around restoring and preserving musculoskeletal function, with a research focus on cartilage injury and repair. His research focuses on developing clinically relevant injury models, including anterior cruciate ligament (ACL) rupture in mice, and seeks to identify key mediators of cartilage degeneration with the goal of being able to externally modulate these signals through surgical, pharmacologic, or environmental interventions.

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Alfred Kuo

MD, PhD

Professor, Department of Orthopaedic Surgery, UCSF; Attending Physician, SFVAHCS

Alfred Kuo graduated from the University of California, Berkeley with a degree in biochemistry; and then went on to receive a PhD in biochemistry and his medical degree at UCSF as part of the Medical Scientist Training Program. He was a resident in orthopaedic surgery and a research fellow at the University of California, Davis before completing a fellowship in lower extremity reconstruction at the Scripps Clinic in San Diego.


Kuo has received numerous awards and has published papers in Osteoarthritis and Cartilage, the Journal of Arthroplasty, the Journal of Bone and Joint Surgery, and the Journal of Cell Biology. Here at UCSF, he works closely with Hubert Kim, MD, PhD at San Francisco Veterans Medical Center and continues his clinical and translational research.

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Amy L. Byers

PhD, MPH

Research Health Science Specialist, SFVAHCS

Professor of Psychiatry and Medicine (Division of Geriatrics), UCSF

Dr. Amy Byers leads an independent program and oversees the Byers Lab. Dr. Byers is a Research Career Scientist at the SFVAHCS, and Professor of Psychiatry & Behavioral Sciences and Medicine (Division of Geriatrics) at UCSF. The Byers Lab focuses on determining the incidence, prevalence, risk factors, and outcomes of late-life mental health disorders and behaviors, with a focus on late-life suicide and neuropsychiatric disorders using large, epidemiologic, and administrative datasets that include national probability samples, VA data, Centers for Medicare and Medicaid Services data, and national suicide attempt and death data. The Byers Lab has been funded by several agencies, including NIH (i.e., NIMH, NIA, and NIMHD), Department of Defense, and VA. Dr. Byers is PI of the first VA R01-level grant longitudinally investigating suicide and suicidal behavior at a national level in older U.S. Veterans. Dr. Byers’ NIH-funded research program currently focuses on suicide and suicide-related behaviors and dementia risk among older Veterans and individuals reentering the community from incarceration. Furthermore, Dr. Byers has been funded by the UCSF’s Older Americans Independence Center to provide innovative methodologic advancements to estimate associations of late-life suicide risk linked to specific medications.

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