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About NCIRE - The Veterans Health Research Institute
NCIRE's Impact on Veterans Veteran's Health Research Researchers by Name
There's no question that the San Francisco VA Medical Center, with the support of NCIRE, plays a major role in advancing veterans health care through research. The excellence of our NCIRE and SFVAMC investigators, all of whom are UC San Francisco faculty members, is fundamental to our success in developing cutting edge knowledge that will advance medical treatments of veterans and others, both locally and worldwide.

Paul Volberding, MD
Chair, NCIRE Board of Directors
Chief of Medicine, SFVAMC

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Grant E. Gauger, MD

Staff Physician, Surgical Service, SFVAMC
Clinical Professor Emeritus of Neurological Surgery, UCSF

Email: grant.gauger@va.gov

Investigating Closed-Head Traumatic Brain Injury

Dr. Gauger has extensive expertise in the treatment of brain and spinal cord injury and neurological trauma. Currently, he is investigating the uses of MRI and diffusion tensor imaging (DTI) to measure changes in the brain in post-concussion. Blunt trauma of the human brain, which occurs in a wide variety of military operations, presents serious problems in assessment, treatment, and outcome prediction. Mild traumatic brain injury - concussion - is frequently followed by a clinical syndrome that is associated with serious disability, despite the absence of significant abnormalities on conventional radiologic imaging. Previous studies of concussion subjects using 1.5 Tesla magnetic resonance imaging have revealed evidence of widespread metabolic changes. In order to clarify the extent and significance of such changes, Dr. Gauger is studying concussion subjects using MRI and DTI data obtained with a higher-resolution 4 Tesla MRI system. This research is anticipated to lead to improved understanding of post-concussion syndrome, with early application to important decisions in the assessment and treatment of injured military personnel.

Govindaraju V, Gauger GE, Manley GT, Ebel A, Meeker M, Maudsley AA. 2004. Volumetric proton spectroscopic imaging of mild traumatic brain injury. AJNR Am J Neuroradiol 25(5):730-7.