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About NCIRE - The Veterans Health Research Institute
NCIRE's Impact on Veterans Veteran's Health Research Researchers by Name
There's no question that the San Francisco VA Medical Center, with the support of NCIRE, plays a major role in advancing veterans health care through research. The excellence of our NCIRE and SFVAMC investigators, all of whom are UC San Francisco faculty members, is fundamental to our success in developing cutting edge knowledge that will advance medical treatments of veterans and others, both locally and worldwide.

Paul Volberding, MD
Chair, NCIRE Board of Directors
Chief of Medicine, SFVAMC

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Alfred C. Kuo, MD, PhD

Staff Physician, Surgical Service, SFVAMC
Assistant Professor in Residence of Orthopedic Surgery, UCSF

Email: Alfred.Kuo@va.gov

Improved Treatment of Injuries to Joint Cartilage

The research in Dr. Kuo's laboratory focuses on the biology of articular (joint) cartilage, including tissue engineering of articular cartilage as well as the mechanisms of trauma and oxidant-induced articular cartilage injury. His work focuses on how cell-based therapies combined with growth factor stimulation may improve the treatment of articular cartilage injuries. Current projects include a study to discover more efficacious treatments to prevent cartilage cell death and a study to develop improved treatments for articular cartilage injuries using tissue engineering.

Kuo AC, Meehan JP, Lee M. 2005.  Knee fusion using dual platings with the locking compression plate. J Arthroplasty 20:772-6.

Kuo AC, Rodrigo JJ, Reddi AH, Curtiss S, Grotkopp E, Chiu M. 2006.  Microfracture and bone morphogenetic protein 7 (BMP-7) synergistically stimulate articular cartilage repair. Osteoarthr Cartilage 14:1126-35.