Research Scientist, Surgical Service, SFVAMC
Assistant Adjunct Professor of Surgery, UCSF

Email: liang.ge@va.gov

Dr. Ge studies the role of blood flow on the development and treatment of a number of cardiovascular diseases, including aneurysm, stenosis, and heart valve disease. As blood flows throughout the heart and blood vessels, it constantly places mechanical forces -- pressure and friction -- on blood cells and vessel walls. Under normal conditions, there is a balance between these forces and the life cycle of the blood cells or vessel walls. Disrupted balance due to abnormal forces acting on blood cells and vessel walls could lead to cardiovascular disease. Dr. Ge has developed advanced mathematical models to study the mechanical forces acting on blood cells and vessel walls under both normal and diseased conditions. These models will help researchers to understand exactly how abnormal mechanical forces lead to cardiovascular disease.

Ge L and Sotiropoulos F. 2007. A numerical method for solving the 3D unsteady incompressible Navier-Stokes equations in curvilinear domains with complex immersed boundaries. Journal of Computational Physics 225(2):1782-1809.

Ge L, Dasi LP, Sotiropoulos F, Yoganathan AP. 2008. Characterization of hemodynamic forces induced by mechanical heart valves: Reynolds vs. viscous stresses. Annals of Biomedical Engineering 36(2):276-297.